A fundamental characteristic shared by cancer cells is the ability to replicate indefinitely—a process that is strongly influenced by epigenetic regulation.
Aggressive tumours often carry defects in their ability to repair DNA, enabling them to accumulate mutations and adapt to the challenging environment.
The ability to hide from the immune system is a well-established hallmark of cancer cells.
Uncontrolled cellular division combined with evasion of apoptosis is a classic hallmark of cancer.
In healthy tissue, antigrowth signals halt the proliferation of cells. Cells bypassing the them are a step closer to becoming cancerous.
Epigenetics is a rapidly growing field of scientific inquiry. It explains how our bodies have just one genetic code, but ~200 different cell types.
As of November 2020, for every 10 women who have lost their lives due to COVID-19, 14 men were reported to succumb to the disease. Are men more at risk?
Once inhaled, our first line of defense against SARS-CoV-2 is the innate immune response—a system that is intimately linked to epigenetics.
Though there is much to learn about this virus and this disease, we know many ways that epigenetics is involved in infection and immunity.
The severity of disease and the inability to fight it off can, in part, be attributed to epigenetic dysregulation of an aging immune system.