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CEEHRC / About Epigenetics /
Welcome to This is Epigenetics—A new CEEHRC Initiative!

CEEHRC—a network of epigenetic scientists and researchers from across Canada—has launched a new knowledge sharing initiative.

What is Epigenetics Cover
What is Epigenetics?

Epigenetics is a rapidly growing field of scientific inquiry. It explains how our bodies have just one genetic code, but ~200 different cell types.

Hossein Davarinejad
Scientist Spotlight: Hossein Davarinejad

Hossein Davarinejad is a Graduate Student in Dr. Jean-François Couture's laboratory at the University of Ottawa. Learn more about Hossein and his research here!

packaging of DNA into chromatin
Chromatin State of Matter Matters: Is It Liquid or Solid?

Over the last decades, there has been much debate regarding chromatin state of matter. Up until recently, chromatin was believed to be liquid.

a graphic of the brain with a chromatin overlay
Neurodevelopment has epigenetics on the brain

The brain is a remarkable organ and one of the most complex to assemble. DNA methylation mediates differentiation and regulation.

elderly hand and baby feet
Intergenerational versus transgenerational epigenetic inheritance: the parental environment

The parental environment can influence the health of subsequent generations through epigenetic inheritance.

ultrasound of pregnant woman's stomach
Lifestyle Choices Influence Reproductive Health Through Epigenetics

The reproductive system’s developmental and functional processes strongly rely on dynamic, yet faithful, epigenetic mechanisms from early development to adulthood. The pre-conception health of men and women, along with the in utero environment, have a direct impact on epigenetic modifications in sperm and oocytes (eggs). Therefore, lifestyle choices are key to safeguarding your health, fertility and the health of future children.

Epigenetic dysregulation enhances cancer cell metabolism

A key characteristic of cancer cells is their ability to adapt their metabolism to their environment, and some of these changes are dependent on epigenetic dysregulation.

Cancer cell
Epigenetic dysregulation ensures tumours are well-fed

In order to grow, proliferate and spread throughout the body, rapidly dividing cancer cells require a constant stream of nutrients and access to the circulatory system.

cancer cell
Targeting cancer cell immortality

A fundamental characteristic shared by cancer cells is the ability to replicate indefinitely—a process that is strongly influenced by epigenetic regulation.