About Epigenetics

Mathias Renaud is a Graduate Student in Dr. Julie Claycomb's laboratory at the University of Toronto. Learn more about Mathias and his research here! 

CEEHRC—a network of epigenetic scientists and researchers from across Canada—has launched a new knowledge sharing initiative.

Hossein Davarinejad is a Graduate Student in Dr. Jean-François Couture's laboratory at the University of Ottawa. Learn more about Hossein and his research here!

Over the last decades, there has been much debate regarding chromatin state of matter. Up until recently, chromatin was believed to be liquid.

The brain is a remarkable organ and one of the most complex to assemble. DNA methylation mediates differentiation and regulation.

The parental environment can influence the health of subsequent generations through epigenetic inheritance.

The reproductive system’s developmental and functional processes strongly rely on dynamic, yet faithful, epigenetic mechanisms from early development to adulthood. The pre-conception health of men and women, along with the in utero environment, have a direct impact on epigenetic modifications in sperm and oocytes (eggs). Therefore, lifestyle choices are key to safeguarding your health, fertility and the health of future children.

A key characteristic of cancer cells is their ability to adapt their metabolism to their environment, and some of these changes are dependent on epigenetic dysregulation.

In order to grow, proliferate and spread throughout the body, rapidly dividing cancer cells require a constant stream of nutrients and access to the circulatory system.

A fundamental characteristic shared by cancer cells is the ability to replicate indefinitely—a process that is strongly influenced by epigenetic regulation.