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Mouse Sperm on a Counting Chamber
Epigenetic alteration of the young dark matter in sperm worsens fertility across two successive generations

Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.

ultrasound of pregnant woman's stomach
Lifestyle Choices Influence Reproductive Health Through Epigenetics

The reproductive system’s developmental and functional processes strongly rely on dynamic, yet faithful, epigenetic mechanisms from early development to adulthood. The pre-conception health of men and women, along with the in utero environment, have a direct impact on epigenetic modifications in sperm and oocytes (eggs). Therefore, lifestyle choices are key to safeguarding your health, fertility and the health of future children.