Over the last decades, there has been much debate regarding chromatin state of matter. Up until recently, chromatin was believed to be liquid.
The brain is a remarkable organ and one of the most complex to assemble. DNA methylation mediates differentiation and regulation.
The parental environment can influence the health of subsequent generations through epigenetic inheritance.
The reproductive system’s developmental and functional processes strongly rely on dynamic, yet faithful, epigenetic mechanisms from early development to adulthood. The pre-conception health of men and women, along with the in utero environment, have a direct impact on epigenetic modifications in sperm and oocytes (eggs). Therefore, lifestyle choices are key to safeguarding your health, fertility and the health of future children.
A key characteristic of cancer cells is their ability to adapt their metabolism to their environment, and some of these changes are dependent on epigenetic dysregulation.
In order to grow, proliferate and spread throughout the body, rapidly dividing cancer cells require a constant stream of nutrients and access to the circulatory system.
A fundamental characteristic shared by cancer cells is the ability to replicate indefinitely—a process that is strongly influenced by epigenetic regulation.
Aggressive tumours often carry defects in their ability to repair DNA, enabling them to accumulate mutations and adapt to the challenging environment.
The ability to hide from the immune system is a well-established hallmark of cancer cells.
Uncontrolled cellular division combined with evasion of apoptosis is a classic hallmark of cancer.