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CEEHRC / About Epigenetics /
Mouse Model
Epigenetics and drug addiction: predisposition, chronic use, relapse and treatment

For those who have not experienced drug addiction, it can be easy to view the disease as a choice—but research shows that epigenetics plays an important role.

Mouse Sperm on a Counting Chamber
Epigenetic alteration of the young dark matter in sperm worsens fertility across two successive generations

Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.

Figure 1
Beyond the Sequence: A Biologist's Roadmap to Epigenomic Analysis

Unlock the complexities of epigenomic data analysis with this comprehensive guide, from quality control to visualization.

Figure
Epigenetic regulation of the life cycles of oncogenic viruses

Oncogenic viruses, viruses that drive cancer, use epigenetics to regulate their life cycles and these epigenetic processes can be disrupted in cancer.

DNA code
From Code to Control: The Therapeutic Potential of Epigenome Editing

Epigenetic editing may outperform gene therapy for complex diseases by controlling, not altering, the genetic code, expanding therapeutic possibilities.

folate epigenetics
We are what we eat: the epigenetic contribution of folic acid during pregnancy

Have you ever wondered why doctors recommend taking folate (also known as folic acid) during pregnancy? Turns out, it's a crucial supplement for the healthy development of growing babies, especially their central nervous system.

galloy
Scientist Spotlight: Maxime Galloy, Université Laval

Maxime Galloy works on deciphering how the chromatin composition surrounding the DNA damage impact the repair.

prostate cancer
Prostate Cancer Lineage Plasticity is Driven by Epigenetic Alterations

Epigenetic plasticity drives castration-resistant prostate cancer (CRPC) to neuroendocrine prostate cancer (NEPC) transition, marked by chromatin remodeling and DNA methylation changes

Oncohistones
Oncohistones; Epigenetic drivers of Cancer and Beyond

This article introduces oncohistones and provides a brief overview of commonly studied oncohistone mutations and their involvement in cancer.