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CEEHRC / About Epigenetics /
Mouse Model
Epigenetics and drug addiction: predisposition, chronic use, relapse and treatment

For those who have not experienced drug addiction, it can be easy to view the disease as a choice—but research shows that epigenetics plays an important role.

Mouse Sperm on a Counting Chamber
Epigenetic alteration of the young dark matter in sperm worsens fertility across two successive generations

Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.

Juan Zhang
Scientist Spotlight: Juan Zhang, University of Toronto

Juan works on repetitive elements for their potential roles in chromatin organization during early embryonic development

Kailynn MacGillivray
Scientist Spotlight: Kailynn MacGillivray, University of Toronto

Kailynn MacGillivray works on histone modifications in C. elegans

Louis-Alexandre Fournier
Scientist Spotlight: Louis-Alexandre Fournier, University of British Columbia

Louis-Alexandre Fournier works on regulation of DNA organization within the cell.

Cat fur and color blindness: what X-chromosome inactivation teaches us about health

The epigenetic inactivation of the X chromosome during embryonic development drives major biological processes – for us and for our favorite pets.

Rachel Price
Scientist Spotlight: Rachel Price, University of British Columbia

Rachel Price's research focuses on transcription factor activity during mitosis in mouse embryonic stem cells.

Epigenetic Control of the Epithelial to Mesenchymal Transition in Cancer Metastasis

Abnormal histone modifications affect expression of key epithelial to mesenchymal transition (EMT) marker genes, driving cancer metastasis.

Benjamin Lebeau
Scientist Spotlight: Benjamin Lebeau, McGill University

Benjamin Lebeau's research focuses on the oncogenic and epigenetic impact of CTCF mutations or copy number loss in breast cancer.