For those who have not experienced drug addiction, it can be easy to view the disease as a choice—but research shows that epigenetics plays an important role.
Loss of DNA methylation at transposable elements in sperm is associated with decreased sperm function in the offspring.
Kailynn MacGillivray works on histone modifications in C. elegans
Louis-Alexandre Fournier works on regulation of DNA organization within the cell.
The epigenetic inactivation of the X chromosome during embryonic development drives major biological processes – for us and for our favorite pets.
Rachel Price's research focuses on transcription factor activity during mitosis in mouse embryonic stem cells.
Abnormal histone modifications affect expression of key epithelial to mesenchymal transition (EMT) marker genes, driving cancer metastasis.
Benjamin Lebeau's research focuses on the oncogenic and epigenetic impact of CTCF mutations or copy number loss in breast cancer.
Dr. Giacomo Grillo is a post doctoral fellow at the University of Toronto where he studies chromatin and transposable element activation in prostate cancer.
Marina Fukano's research focuses on the consequences of metabolic heterogeneity on the progression and drug response of triple-negative breast tumors.