POSITION OVERVIEW:
The postdoctoral fellow will work in a multidisciplinary team investigating epigenetic processes in brain normal and disease states (Rett syndrome). The projects investigate the genomic landscape of DNA and histone modifications. The project will be done jointly in Dr Mojgan Rastegar’s and Dr Jim Davie’s Labs in the Department of Biochemistry and Medical Genetics, University of Manitoba. This position will initially be for 1 year, and based on performance, be expended for several more years.
QUALIFICATIONS AND EDUCATION REQUIREMENTS
- PhD in Biochemistry, Molecular Biology or related field.
- Strong background in epigenomic research with expertise in chromatin immunoprecipitation (ChIP) assay and ChIP-Seq.
- DNA and RNA analyses
- Experience with gene editing (CRISPR-Cas9), and chromatin accessibility assays are a plus.
DEPARTMENT DESCRIPTION
The Department of Biochemistry and Medical Genetics is located on the Bannatyne Campus, the main medical and health sciences campus of the University of Manitoba. The department is home to biochemistry, molecular biological sciences, and medical genetics expertise, practiced in an intellectually enriching research and teaching environment in the Max Rady College of Medicine and Faculty of Graduate Studies.
The Rastegar lab explores epigenetic control of brain development, stem cell differentiation, and neurodevelopmental disorders including Rett Syndrome. Her research team focuses on the role of DNA methylation reader, MeCP2, in determining neuronal structure and function using different model systems.
The Davie lab explores the role of chromatin modifiers in regulating gene expression. His research group has a long-term interest in chromatin structure/function, epigenetic regulation, nuclear matrix, nuclear organization, and chromatin modifying enzymes including histone deacetylases, kinases, methyltransferases, and histone modifications.
HOW TO APPLY? Interested applicants should send their applications as one single .pdf file to Dr Jim Davie (Jim.davie@umanitoba.ca), with the following information:
- The subject of the email should be "Postdoc NeuroEpigenBMG"
- Two-page CV
- Publication List
- One page Research Summary
ABOUT THE CITY
Manitoba encompasses prairie, boreal plains, boreal shield, taiga shield, Hudson plains, and southern arctic ecozones offering a wide range of research as well as recreational opportunities. The City of Winnipeg (www.tourismwinnipeg.com), located where the Red and Assiniboine Rivers meet, is recognized for its vibrant, multicultural community and diverse culture. With a growing population of more than 766,000, the city is home to internationally renowned festivals, galleries, and museums, the historic Exchange District and The Forks, and ever-expanding research, education, and business sectors. The City boasts a lively arts scene, including a major symphony orchestra, the Royal Winnipeg Ballet, and Qaumajuq - the Inuit Art Centre at the Winnipeg Art Gallery.
